Reproduction Abstracts

Introduction: Environmental chemicals (ECs) are associated with an increased incidence of testicular cancer and reduced sperm quality. Regional differences are thought to reflect different levels of EC exposure. Since the dog is a sentinel of human exposure, we hypothesised that geographical variation in testicular chemical profiles may be associated with altered reproductive development and/or function.Methods: Canine adult testes (routine castrations) ...

Introduction: Declining human and canine male fertility has been associated with exposure to environmental chemicals (ECs). We investigated the effects of ECs on canine and human sperm vitality, motility, and morphology.Methods: Mean canine testicular levels (MTL) of PCB153 and DEHP were 0.9±0.14 μg/kg (n=8) and 0.31±0.03 μg/g (n=5) respectively. Spermatozoa from dogs (n=7) and human donations (n=9,...